[HTML][HTML] Evidence for Multiple Activators for Stress-activated Protein Kinases/c-Jun Amino-terminal Kinases.: EXISTENCE OF NOVEL ACTIVATORS∗
T Moriguchi, H Kawasaki, S Matsuda, Y Gotoh… - Journal of Biological …, 1995 - ASBMB
Stress-activated protein kinases (SAPKs) or c-Jun amino-terminal kinases (JNKs), which
belong to a subgroup of the mitogen-activated protein kinase (MAPK) superfamily, are
activated in response to a variety of stresses in mammalian cells. An activity to activate a
recombinant rat SAPKα was detected in extracts obtained from rat fibroblastic 3Y1 cells
exposed to hyperosmolar media and was resolved into unadsorbed and adsorbed fractions
on Q-Sepharose chromatography. The adsorbed activity was identified as …
belong to a subgroup of the mitogen-activated protein kinase (MAPK) superfamily, are
activated in response to a variety of stresses in mammalian cells. An activity to activate a
recombinant rat SAPKα was detected in extracts obtained from rat fibroblastic 3Y1 cells
exposed to hyperosmolar media and was resolved into unadsorbed and adsorbed fractions
on Q-Sepharose chromatography. The adsorbed activity was identified as …
