Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs
T Tobimatsu, H Fujisawa - Journal of Biological Chemistry, 1989 - ASBMB
cDNA clones for a fifth polypeptide of rat brain calmodulin-dependent protein kinase II were
isolated and sequenced. The cDNA sequence encoded a polypeptide, designated δ,
consisting of 533 amino acid residues with a molecular weight of 60,080. Comparison of
amino acid sequences of this and α, β, β‵, and γ polypeptides of calmodulin-dependent
protein kinase II reveals marked homology among them. The mRNAs for δ were expressed
in rat brain tissues with different regional specificities. The distribution of α, β/β‵, γ, and δ …
isolated and sequenced. The cDNA sequence encoded a polypeptide, designated δ,
consisting of 533 amino acid residues with a molecular weight of 60,080. Comparison of
amino acid sequences of this and α, β, β‵, and γ polypeptides of calmodulin-dependent
protein kinase II reveals marked homology among them. The mRNAs for δ were expressed
in rat brain tissues with different regional specificities. The distribution of α, β/β‵, γ, and δ …