Diseases of the mitochondrial DNA
DC Wallace - Annual review of biochemistry, 1992 - annualreviews.org
DC Wallace
Annual review of biochemistry, 1992•annualreviews.orgDISEASES OF THE MITOCHONDRIAL DNA Page 1 Anna. Rev. Biochem. 1992. 61:1175-1212
Copyright İ 1992 by Annual Review,' Inc. All rights reserved DISEASES OF THE
MITOCHONDRIAL DNA Douglas C. Wallace Department of Genetics and Molecular Medicine,
Emory University School of Medicine, 1462 Clifton Road, Atlanta, Georgia 30322 KEY
WORDS: mitochondrial diseases, oxidative phosphorylation. maternal inheritance. de
generative diseases, aging CONTENTS INTRODUCTION …
Copyright İ 1992 by Annual Review,' Inc. All rights reserved DISEASES OF THE
MITOCHONDRIAL DNA Douglas C. Wallace Department of Genetics and Molecular Medicine,
Emory University School of Medicine, 1462 Clifton Road, Atlanta, Georgia 30322 KEY
WORDS: mitochondrial diseases, oxidative phosphorylation. maternal inheritance. de
generative diseases, aging CONTENTS INTRODUCTION …
Over the past three years, a number of mitochondrial DNA (mtDNA) muta tions that cause human disease have been identified. These are associated with
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