cag+Helicobacter pylori Induces Homotypic Aggregation of Macrophage-Like Cells by Up-Regulation and Recruitment of Intracellular Adhesion Molecule 1 to the …
Infection with cag+ but not cag-negative Helicobacter pylori leads to the formation of large
homotypic aggregates of macrophage-like cells. Intracellular adhesion molecule 1 is up-
regulated and recruited to the cell surface of infected cells and mediates the aggregation via
lymphocyte function-associated molecule 1. This signaling may regulate cell-cell
interactions and inflammatory responses.
homotypic aggregates of macrophage-like cells. Intracellular adhesion molecule 1 is up-
regulated and recruited to the cell surface of infected cells and mediates the aggregation via
lymphocyte function-associated molecule 1. This signaling may regulate cell-cell
interactions and inflammatory responses.
Abstract
Infection with cag+ but not cag-negative Helicobacter pylori leads to the formation of large homotypic aggregates of macrophage-like cells. Intracellular adhesion molecule 1 is up-regulated and recruited to the cell surface of infected cells and mediates the aggregation via lymphocyte function-associated molecule 1. This signaling may regulate cell-cell interactions and inflammatory responses.
American Society for Microbiology