Hippocampal formation: anatomy and the patterns of pathology in Alzheimer's disease

GW Van Hoesen, BT Hyman - Progress in brain research, 1990 - Elsevier
Anatomical studies of the primate brain have shown that the subicular and CA1 allocortices
give rise to hippocampal efferents that course to numerous telencephalic and diencephalic
targets including other parts of the cortex. The hippocampal formation is damaged heavily in
Alzheimer's disease, and is a focal point for pathology. We examined the anteroposterior
extent of the hippocampal formation in 52 cases of Alzheimer's disease, 6 cases of other
types of dementia and 10 age-compatible controls, to determine the patterns of pathology …