Immunomodulatory effect of interleukin-16 on allergic airway inflammation
FF Little, J de Bie, A van Oosterhout, H Kornfeld… - Chest, 2003 - journal.chestnet.org
Abbreviations: AHR airway hyperresponsiveness; IL interleukin; Th2 T-helper type 2 Atopy is
characterized by dysregulated T-helper type 2 (Th2) lymphocyte activation and cytokine
synthesis. This aberrant immune response, when present in the lung, leads to the cardinal
pathologic and physiologic features of asthma. Interleukin (IL)-16 is a pleiotropic cytokine
that uses CD4 as its receptor and has
characterized by dysregulated T-helper type 2 (Th2) lymphocyte activation and cytokine
synthesis. This aberrant immune response, when present in the lung, leads to the cardinal
pathologic and physiologic features of asthma. Interleukin (IL)-16 is a pleiotropic cytokine
that uses CD4 as its receptor and has