Pou2f3/Skn-1a is necessary for the generation or differentiation of solitary chemosensory cells in the anterior nasal cavity
M Ohmoto, T Yamaguchi, J Yamashita… - Bioscience …, 2013 - academic.oup.com
M Ohmoto, T Yamaguchi, J Yamashita, AA Bachmanov, J Hirota, I Matsumoto
Bioscience, biotechnology, and biochemistry, 2013•academic.oup.comSolitary chemosensory cells in the non-neuronal epithelium of the anterior nasal cavity have
bitter taste cell-like molecular characteristics and are involved in the detection of noxious
substances. Here, we demonstrate that Pou2f3/Skn-1a, which is necessary for generation of
sweet, umami, and bitter taste cells, is also necessary for the generation or differentiation of
solitary chemosensory cells.
bitter taste cell-like molecular characteristics and are involved in the detection of noxious
substances. Here, we demonstrate that Pou2f3/Skn-1a, which is necessary for generation of
sweet, umami, and bitter taste cells, is also necessary for the generation or differentiation of
solitary chemosensory cells.
Abstract
Solitary chemosensory cells in the non-neuronal epithelium of the anterior nasal cavity have bitter taste cell-like molecular characteristics and are involved in the detection of noxious substances. Here, we demonstrate that Pou2f3/Skn-1a, which is necessary for generation of sweet, umami, and bitter taste cells, is also necessary for the generation or differentiation of solitary chemosensory cells.
Oxford University Press