[HTML][HTML] Distinct expression patterns of alveolar “alarmins” in subtypes of chronic lung allograft dysfunction

T Saito, M Liu, M Binnie, M Sato, D Hwang… - American Journal of …, 2014 - Elsevier
The long-term success of lung transplantation is limited by chronic lung allograft dysfunction
(CLAD). The purpose of this study was to investigate the alveolar alarmin profiles in CLAD
subtypes, restrictive allograft syndrome (RAS) and bronchiolitis obliterans syndrome (BOS).
Bronchoalveolar lavage (BAL) samples were collected from 53 recipients who underwent
double lung or heart-lung transplantation, including patients with RAS (n= 10), BOS (n= 18)
and No CLAD (n= 25). Protein levels of alarmins such as S100A8, S100A9, S100A8/A9 …