Characterisation of the humoral immune response during murine pregnancy
DM Dillon, C Cunningham, WT Melvin… - Journal of reproductive …, 1988 - Elsevier
Blood samples from female C57BL/10 mice mated with CBA/Ca males were obtained
before, during and after both first and second pregnancies. A cellular enzyme-linked
immunospecific assay (CELISA) was used to detect maternal antibodies against antigens on
paternal splenocytes. Alloantibodies were detected in 48% of mice during or 9 days after a
first pregnancy and in 82% of mice by the ninth day after the second pregnancy; these
antibodies were first observed on day 10 of the first pregnancy. In two of four active …
before, during and after both first and second pregnancies. A cellular enzyme-linked
immunospecific assay (CELISA) was used to detect maternal antibodies against antigens on
paternal splenocytes. Alloantibodies were detected in 48% of mice during or 9 days after a
first pregnancy and in 82% of mice by the ninth day after the second pregnancy; these
antibodies were first observed on day 10 of the first pregnancy. In two of four active …
