Incidence and risk factors of anti-HLA immunization after pregnancy

E Masson, C Vidal, M Deschamps, S Bongain… - Human immunology, 2013 - Elsevier
Pregnancy is the only natural source of anti-HLA immunization. The exact frequency of this
immunization remains undetermined as prior studies either used methods with a low
sensitivity or were performed late after delivery. We present here the first study on women at
delivery evaluating anti-HLA immunization by Luminex. We also attempted to isolate factors
influencing immunization, such as soluble HLA-G (sHLA-G) levels and genetic
polymorphisms. With Luminex, anti-HLA immunization was observed in 54.4% of the …