[HTML][HTML] National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: IIa. The 2020 clinical …
CL Kitko, J Pidala, HM Schoemans… - … and cellular therapy, 2021 - Elsevier
Recognition of the earliest signs and symptoms of chronic graft-versus-host disease (GVHD)
that lead to severe manifestations remains a challenge. The standardization provided by the
National Institutes of Health (NIH) 2005 and 2014 consensus projects has helped improve
diagnostic accuracy and severity scoring for clinical trials, but utilization of these tools in
routine clinical practice is variable. Additionally, when patients meet the NIH diagnostic
criteria, many already have significant morbidity and possibly irreversible organ damage …
that lead to severe manifestations remains a challenge. The standardization provided by the
National Institutes of Health (NIH) 2005 and 2014 consensus projects has helped improve
diagnostic accuracy and severity scoring for clinical trials, but utilization of these tools in
routine clinical practice is variable. Additionally, when patients meet the NIH diagnostic
criteria, many already have significant morbidity and possibly irreversible organ damage …