[HTML][HTML] Mechanisms responsible for the compositional heterogeneity of nascent high density lipoprotein
S Lund-Katz, NN Lyssenko, M Nickel, D Nguyen… - Journal of Biological …, 2013 - ASBMB
Apolipoprotein (apo) AI-containing nascent HDL particles produced by the ATP binding
cassette transporter A1 have different sizes and compositions. To understand the molecular
basis for this heterogeneity, the HDL particles produced by apoA-I-mediated solubilization of
phospholipid (PL)/free (unesterified) cholesterol (FC) bilayer membranes in cell and cell-free
systems are compared. Incubation of apoA-I with ATP binding cassette transporter A1-
expressing baby hamster kidney cells leads to formation of two populations of FC-containing …
cassette transporter A1 have different sizes and compositions. To understand the molecular
basis for this heterogeneity, the HDL particles produced by apoA-I-mediated solubilization of
phospholipid (PL)/free (unesterified) cholesterol (FC) bilayer membranes in cell and cell-free
systems are compared. Incubation of apoA-I with ATP binding cassette transporter A1-
expressing baby hamster kidney cells leads to formation of two populations of FC-containing …