Propranolol versus captopril in the treatment of infantile hemangioma (IH): a randomized controlled trial
Background Renin-angiotensin system components have been demonstrated in the biology
of infantile hemangioma (IH). Captopril, an angiotensin-converting enzyme inhibitor, is
proposed as a therapeutic alternative to oral propranolol. Objectives We sought to compare
the benefit of propranolol and captopril in the treatment of IH, and to assess angiotensin-
converting enzyme gene polymorphism in patients with IH and in control subjects. Methods
Thirty patients with IH and 35 healthy control subjects were enrolled in this study. Patients …
of infantile hemangioma (IH). Captopril, an angiotensin-converting enzyme inhibitor, is
proposed as a therapeutic alternative to oral propranolol. Objectives We sought to compare
the benefit of propranolol and captopril in the treatment of IH, and to assess angiotensin-
converting enzyme gene polymorphism in patients with IH and in control subjects. Methods
Thirty patients with IH and 35 healthy control subjects were enrolled in this study. Patients …
