Risk for PHACE syndrome in infants with large facial hemangiomas

AN Haggstrom, MC Garzon, E Baselga… - …, 2010 - publications.aap.org
OBJECTIVES: This study was conducted to determine the prevalence of posterior fossae of
the brain, arterial anomalies, cardiac anomalies, and eye anomalies (PHACE) in infants with
large facial hemangiomas. The extracutaneous manifestations of PHACE may be associated
with significant morbidity, and the prevalence of PHACE in patients with facial hemangiomas
has not previously been reported. METHODS: A multicenter prospective study was
conducted with 108 infants who had large facial hemangiomas and were systematically …